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DeCS
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Descriptor English:
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GTP Cyclohydrolase
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Descriptor Spanish:
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GTP Ciclohidrolasa
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Descriptor Portuguese:
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GTP Cicloidrolase
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Synonyms English:
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GTP 8-Formylhydrolase
GTP Dihydrolase
GTP Ring-Opening Enzyme
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Tree Number:
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D08.811.277.151.300
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Definition English:
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(GTP cyclohydrolase I) or GTP 7,8-8,9-dihydrolase (pyrophosphate-forming) (GTP cyclohydrolase II). An enzyme group that hydrolyzes the imidazole ring of GTP, releasing carbon-8 as formate. Two C-N bonds are hydrolyzed and the pentase unit is isomerized. This is the first step in the synthesis of folic acid from GTP. EC 3.5.4.16 (GTP cyclohydrolase I) and EC 3.5.4.25 (GTP cyclohydrolase II). |
History Note English:
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91(75); was see under AMINOHYDROLASES 1975-90
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Allowable Qualifiers English:
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Record Number:
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6285
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Unique Identifier:
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D006136
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Occurrence in VHL:
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Similar:
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DeCS CID-10 SciELO LILACS LIS
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